SSRIs act as Selective Brain Steroidogenic Stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake (2009)

Brain principal glutamatergic neurons synthesize 3?-hydroxy-5?-pregnan-20-one (Allo), a neurosteroid that potently, positively, and allosterically modulates GABA action at GABA[A] receptors. Cerebrospinal fluid (CSF) Allo levels are decreased ...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670606/

About Robert Zinn

Robert Zinn, M.D., Ph.D. is a medical doctor, physician, and web entrepreneur, who, for over 15 years was employed by academic and research institutions and focused his clinical practices on very specialized patient populations, such as those with rare genetic diseases or rare cancers. He shares his knowledge through his website, NutritionTheory.org

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