The Effect of Diaphragmatic Breathing on Attention, Negative Affect and Stress in Healthy Adults (2017)

A growing number of empirical studies have revealed that diaphragmatic breathing may trigger body relaxation responses and benefit both physical and mental health. However, the specific benefits of diaphragmatic breathing on mental health remain largely ...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455070/

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Project4Awesome is live: act now to help life extension

Project4Awesome, the initiative by the Foundation to Decrease Worldsuck that I posted about two days back, is now live. What it means in short is that, if you are able to upload videos to a YouTube?

https://rejuvenaction.wordpress.com/2017/12/15/project4awesome-is-live-act-now-to-help-life-extension/

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Modelling estimates of the burden of respiratory syncytial virus infection in children in the UK [BMJ Open, Jun 2016 — free full-text]

Objective The burden of respiratory syncytial virus (RSV) illness is not well characterised in primary care. We estimated the burden of disease attributable to RSV in children in the UK between 1995 and 2009. Design Time-series regression modelling. Setting A multiple linear regression model based on weekly viral surveillance (RSV and influenza, Public Health England), and controlled for non-specific seasonal drivers of disease, estimated the proportion of general practitioner (GP) episodes of care (counted as first visit in a series within 28?days; Clinical Practice Research Datalink, CPRD), hospitalisations (Hospital Episode Statistics, HES) and deaths (Office of National Statistics, ONS) attributable to RSV each season. Participants Children 0?17?years registered with a GP in CPRD, or with a respiratory disease outcome in the HES or ONS databases. Primary outcome measures RSV-attributable burden of GP episodes, hospitalisations and deaths due to respiratory disease by age. RSV-attributable burden associated with selected antibiotic prescriptions. Results RSV-attributable respiratory disease in the UK resulted in an estimated 450?158 GP episodes, 29?160 hospitalisations and 83 deaths per average season in children and adolescents, with the highest proportions in children <6?months of age (14?441/100?000 population, 4184/100?000 and 6/100?000, respectively). In an average season, there were an estimated 125?478 GP episodes for otitis media and 416?133 prescriptions for antibiotics attributable to RSV. More GP episodes, hospitalisations and deaths from respiratory disease were attributable to RSV than to influenza in children under 5?years. Conclusions The burden of RSV in children in the UK exceeds that of influenza. RSV in children and adolescents contributes substantially to GP office visits for a diverse range of illnesses, and was associated with an average 416?133 prescribed antibiotic courses per season. Effective antiviral treatments and preventive vaccines are urgently needed for the management of RSV infection in children. Trial registration number NCT01706302.

http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2015-009337

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Development and validation of a climate-based ensemble prediction model for West Nile Virus infection rates in Culex mosquitoes, Suffolk County, New York [Parasit Vectors., Aug 2016 — free full-text]

West Nile Virus (WNV) is an endemic public health concern in the United States that produces periodic seasonal epidemics. Underlying these outbreaks is the enzootic cycle of WNV between mosquito vectors and bird hosts. Identifying the key environmental conditions that facilitate and accelerate this cycle can be used to inform effective vector control. Here, we model and forecast WNV infection rates among mosquito vectors in Suffolk County, New York using readily available meteorological and hydrological conditions. We first validate a statistical model built with surveillance data between 2001 and 2009 (m09) and specify a set of new statistical models using surveillance data from 2001 to 2012 (m12). This ensemble of new models is then used to make predictions for 2013–2015, and multimodel inference is employed to provide a formal probabilistic interpretation across the disparate individual model predictions. The findings of the m09 and m12 models align; with the ensemble of m12 models indicating an association between warm, dry early spring (April) conditions and increased annual WNV infection rates in Culex mosquitoes. This study shows that real-time climate information can be used to predict WNV infection rates in Culex mosquitoes prior to its seasonal peak and before WNV spillover transmission risk to humans is greatest.

http://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1720-1

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